BioPharmaSpec has a strong reputation for comprehensive and ICH compliant ADC characterization. ADCs are antibody based products and consist of monoclonal antibodies attached to a cytotoxic drug via a linker, thus combining the cell targeting of the monoclonal antibody with the cell killing ability of the cytotoxic drug.

BioPharmaSpec routinely tests a wide range of ADCs, including Lysine and Cysteine linked conjugates. We can fully characterize the structural and physicochemical attributes of the monoclonal antibody as follows:

Structural Characterization

Physicochemical Characterization

In addition to the above, BioPharmaSpec has further methods specific to ADC characterization: