BioPharmaSpec provides a complete solution for Etanercept/ Enbrel comparability, biosimilarity and characterization studies.
Etanercept (trade name Enbrel) is a recombinant protein made by fusing the TNF-receptor and the constant region of the IgG1 antibody. It is a large biopharmaceutical with a molecular weight of 150 kDa that, similar to Humira, Simponi and Remicade, inhibits tumor necrosis factor alpha (TNFα). TNFα is central to the inflammatory response and plays a major role in inflammatory/ autoimmune diseases such as arthritis, plaque psoriasis and ankylosing spondylitis. Etanercept is therefore used to treat certain inflammatory diseases.