BioPharmaSpec provides a complete solution for Adalimumab/ Humira comparability, biosimilarity and characterization studies.
Adalimumab (trade name Humira) is a monoclonal antibody used in the treatment of arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis and other inflammatory disorders. It is a standard IgG1 antibody that, similar to Enbrel, Simponi and Remicade, inhibits tumor necrosis factor alpha (TNFα). TNFα is central to the inflammatory response and plays a major role in inflammatory/ autoimmune diseases such as arthritis, plaque psoriasis and ankylosing spondylitis. Adalimumab is therefore used to treat certain inflammatory diseases due to this ability to inhibit TNFα.