BioPharmaSpec provides a complete solution for Golimumab/ Simponi comparability, biosimilarity and characterization studies.
Golimumab (trade name Simponi) is a monoclonal antibody used in the treatment of arthritis, ankylosing spondylitis and ulcerative colitis. It is a standard IgG1 antibody that, similar to Enbrel, Humira and Remicade, inhibits tumor necrosis factor alpha (TNFα). TNFα is central to the inflammatory response and plays a major role in inflammatory/ autoimmune diseases such as arthritis, plaque psoriasis and ankylosing spondylitis. Golimumab is therefore used to treat certain inflammatory diseases due to this ability to inhibit TNFα.