It may seem strange to use plant cells when they are so clearly different in their glycoprotein production machinery. However, plant cells do offer some production advantages that manufacturers are keen to make use of.
By their very nature, plant cell systems are different to mammalian cells and thus will not contain animal derived material or indeed animal pathogens. They are also relatively quick and inexpensive to grow or culture, requiring minimal media components and simple culture conditions. However, factors such as plant pathogens, toxic alkaloids and phenols, pesticides and fertilizers impact on the subsequent purification processes.
The ability of plant cells to perform complex bioprocessing tasks such as glycosylation, folding and disulfide bridge formation also gives them an advantage over the use of bacterial systems, which may be advantageous depending on the product being manufactured.