Dendritech, a leading dendrimer production and specialty polymer company, is focused solely on the development and larger-scale production of tailor-made dendrimer and hyperbranched polymers. Their PAMAM (polyamidoamine) dendrimers have exceptional molecular uniformity, compact nanoscopic size, globular shape and high surface group functionality.

With more than 20 years of dendrimer product research and development and with state-of-the-art manufacturing capabilities, Dendrimer work to create value-added solutions for their customers.

Project Overview

Dendritech required molecular weight data for multiple batches of various PAMAM dendrimers in order to support developmental and quality related decisions. BioPharmaSpec performed Mass Spectrometric analysis (MALDI-TOF) of each supplied sample.

Technical Considerations- Molecular Weight

Due to the complexity and specific chemical nature of PAMAM dendrimers, MALDI-TOF proved to be the ideal analytical technique to deal with analysis of the intact polymers. BioPharmaSpec’s expertise ensured proper differentiation between forms of the polymer material.

Client testimonial

We could not be happier with the service and attention that we have received from the folks at BioPharmaSpec, Inc. We contacted BioPharmaSpec because our previous analytical partner informed us that lead-times and costs for sample analysis were going to increase. BioPharmaSpec has given us consistent turnaround times, competitive costs, and has also demonstrated specific technical expertise in analyzing some of our higher molecular weight samples that our previous partner could not. I have nothing but good things to say about BioPharmaSpec and would recommend them to anyone. – Chemist/Lab Manager, Dendritech, Inc.