OCT 21, 2021 9:00 AM PDT/ 12PM EDT/ 5PM BST
Industry guidelines for host cell protein impurity analysis
emphasize the importance of process-specific and product-specific assessment to account for how the purification procedures
and the therapeutic product may uniquely influence the impurities observed. HCP-Mass Spectrometry (HCP-MS) analysis is quickly becoming recognized as a practical, orthogonal approach
to ELISA to achieve greater coverage
and knowledge of the HCP profile of a biopharmaceutical product.
Establishing a streamlined workflow for HCP-MS analysis can be challenging, given that the strategies and rationale for implementing HCP-MS will differ depending on the product, process(es) and other project-specific variables. This webinar will highlight the benefits and the limitations of key analysis criteria for scientists who are developing their HCP-MS detection strategy.
- Identify the workflows for HCP-MS impurity analysis
- Discuss the advantages of different spectral library types
- Analyze the quantitative MS data processing methods and approaches from SWATH Acquisition on the SCIEXTripleTOF 6600 system
- Discover our guide for sample selection for HCP quantitation