AAV (Adeno Associated Viruses)
Categories:
Definition
Adeno-associated viruses are small (approx. 20nm) viruses that infect humans and some other primates. The AAV capsid packages a single-stranded (ssDNA) genome of approx. 4.7kb in length. In the field of Gene Therapy, recombinant adeno-associated viruses (rAAVs) are the most widely used delivery vectors for therapeutic administration of transgenes due to their high transduction efficiency, high levels of gene expression and favorable safety profile.