Antibody Drug Conjugate (ADC)

Categories: Glossary: Biopharmaceuticals

Definition

Antibody Drug Conjugates (ADCs) are antibody-based, anti-cancer biopharmaceuticals consisting of monoclonal antibodies attached to a cytotoxic drug (or payload) via a linker.

Related Content & Resources

Knowledge Center

Technical Poster: Structural and Physicochemical Characterization of Antibody Drug Conjugates (ADCs) See Here
From ADCs to XDCs: The Evolution of Conjugate Therapeutics Read More
How Antibody-Drug Conjugates Work: Mechanism of Action and Analytical Considerations Read More

Case Study

Iksuda Therapeutics – Assessment of Drug Antibody Ratios (DARs)

Iksuda requested an assessment of DARs for their antibody-drug-conjugate (ADC) product in plasma samples derived from mouse Pharmacokinetic (PK) studies.