Coefficient of Variation (CV)

Categories: host cell protein , impurities

Definition

Coefficient of Variation (CV) is the ratio of the standard deviation to the mean. The higher the CV, the greater the level of dispersion around the mean. It is generally expressed as a percentage.

Related Content & Resources

Knowledge Center

On Demand Webinar: Characterizing Protein Impurities WATCH NOW
Thinking About LC-MS for HCP Quantitation? Read More

Case Study

Sekisui – Method Development for a Process Related Residual

An on-line LC/ES-MS method for pDADMAC analysis was developed. Initial mass spectrometric investigations identified key ions shown to be suitable for a quantitative analysis of pDADMAC through a Multiple Reaction Monitoring approach.