Critical Quality Attributes (CQAs)

Definition

ICH Q8 (R2) defines this: “A CQA is a physical, chemical, biological, or microbiological property or characteristic that should be within an appropriate limit, range, or distribution to ensure the desired product quality. CQAs are generally associated with the drug substance, excipients, intermediates (in-process materials) and drug product.”
https://database.ich.org/sites/default/files/Q8%28R2%29%20Guideline.pdf