Drug-to-Antibody Ratio (DAR)

Categories: biopharmaceuticals

Definition

The distribution of different payload attachments (the cytotoxic drug) to an Antibody-Drug Conjugate (ADC), or the average of different drug to antibody loads for an ADC.

Related Content & Resources

Case Study

Iksuda Therapeutics – Assessment of Drug Antibody Ratios (DARs)

Iksuda requested an assessment of DARs for their antibody-drug-conjugate (ADC) product in plasma samples derived from mouse Pharmacokinetic (PK) studies.

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