Glycosylation
Categories:
Glossary: Glycosylation
Definition
Glycosylation is the attachment of carbohydrates to the backbone of a protein through an enzymatic reaction. A protein that is glycosylated is known as a glycoprotein. The two most common types of protein glycosylation are known as N-glycosylation and O-glycosylation. Of these two forms of glycosylation, N-glycosylation is the most commonly found.
Related Content & Resources
Case Study
Iksuda Therapeutics – Oligosaccharide Profiling of an ADC
Iksuda required glycosylation analysis for their Antibody Drug Conjugate product to provide functionally important post-translational modification information and to ensure that the chemistry used to attach the drug did not impact glycosylation.
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