N-terminal Sequencing

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Definition

Also known as gas phase sequencing, Edman sequencing or Edman degradation, N-terminal sequencing is an experimental procedure which will allow determination of the N-terminal residue(s) of your biopharmaceutical or peptide.

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Case Study

MedImmune – N-Terminal Sequencing

BioPharmaSpec performed N-terminal sequencing analysis of bands observed on SDS-PAGE gels from various protein samples, in order to provide truncation site data that could be used in the planning of potential product improvements.

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