Polyethylene glycol (PEG)

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Definition

Polyethylene glycol, or PEG, is a synthetic polymer that is attached to certain biopharmaceuticals during production, usually in order to suppress potential immunogenicity or prolong the half-life over the native protein.

Related Content & Resources

Knowledge Center

Scientific Article: Dealing with the challenges of post translational modification (PTMs) Read More

Case Study

Intas Pharmaceuticals Ltd.- Structural Characterization of PEG-GCSF Using Nuclear Magnetic Resonance (NMR)

ICH Topic Q6B includes the use of NMR as a tool for understanding higher order structure. Here, BioPharmaSpec characterizes several samples of PEG-GCSF using 1-Dimensional (1D) 1H-NMR and 2-Dimensional (2D) 1H/13C-NMR at 800MHz.