Our Instrumentation

State-of-the-art instrumentation for protein characterization

Mass Spectrometry

  • Waters Cyclic Ion Mobility Separation High Definition Mass Spectrometer with ECD
  • Waters Xevo MRT Mass Spectrometer with Acquity Premier
  • Sciex ZenoTOF 7600 LC-MS/MS Systems with EAD
  • Waters Xevo TQ Absolute Mass Spectrometer, API Unispray source & dedicated APCI probe
  • Waters Xevo G3 Q-TOF Mass Spectrometers, Acquity Premier UPLC
  • Sciex TripleTOF 6600 QTOF Mass Spectrometer
  • Waters Xevo G2-XS Q-TOF Mass Spectrometers, ES & Nanospray
  • Waters Xevo TQ-S Mass Spectrometers, ES
  • Waters Xevo G2 Q-TOF Mass Spectrometers, ES & Nanospray
  • Sciex 5800 MALDI TOF/TOF Mass Spectrometers

Chromatography

  • Waters Acquity UPLC (w/ PDA detector)
  • Waters Acquity Premier UPLC Systems (w/ PDA detector)
  • Waters Acquity I-Class UPLC (w/PDA detector)
  • Waters Acquity H-Class Bio UPLC (w/PDA and Fluorescence detectors)
  • Waters Acquity APC p-QSM Core HPLC (w/ ELS Detector)
  • Agilent 1260 HPLC
  • Perkin Elmer Clarus 680 GC/MS with Headspace sampler
  • Aggregation
    • Wyatt DAWN MALS (with integrated DLS/QELS) and Optilab dRI detector

Protein Sequencer

Isoelectric Focusing

  • Charge isoform analysis
    • Protein Simple MauriceFlex Complete Imaged Capillary System (running icIEF, CE-SDS and cIEF fractionation)
    • ProteinSimple Maurice CE-SDS

BioPhysical Characterization

  • Higher Order Structure
    • Nuclear Magnetic Resonance (NMR)- Bruker DRX800
    • Jasco V-750 UV-Vis/NIR Spectrophotometer
    • Jasco J-1500 Circular Dichroism Spectropolarimeter
    • Jasco FT-IR 4600 Spectrometer
    • Jasco FP-8300 Spectrofluorimeter
    • Differential Scanning Calorimeter (DSC)
    • Wyatt DynaPro Plate Reader III (Dynamic Light Scattering, DLS)
    • RedShiftBio Aurora TX- Microfluidic Modulation Spectroscopy (MMS)
  • Aggregation
    • Beckman Coulter Optima AUC, XL-I and XL-A instruments
    • o Wyatt DAWN MALS (with integrated DLS/QELS) and Optilab dRI detector

Make our labs an extension of your labs.