On Demand Webinar: Understanding the Importance of Higher Order Protein Structure

Biophysical and Physicochemical Techniques for Comprehensive Characterization of Aggregation Profiles and Secondary and Tertiary Structure

Changes to the higher order structure of your biopharmaceutical can have detrimental effects on the safety, stability, function and immunogenicity of the product.

This webinar will detail the key analytical techniques used to assess the higher order structure of biopharmaceuticals and therefore define potential Critical Quality Attributes (CQAs).

Case studies from representative antibody products will include example data from:

  • Circular Dichroism (CD)
  • Fourier Transform Infrared Spectroscopy (FT-IR)
  • Fluorescence
  • Nuclear Magnetic Resonance (NMR)
  • Sedimentation Velocity Analytical UltraCentrifugation (SV-AUC)
  • Size Exclusion Chromatography- Multi-Angle Light Scattering (SEC-MALS)

Watch this webinar now and join BioPharmaSpec experts, as we share our experiences and expertise in the biophysical and physicochemical characterization of proteins.