BioPharmaSpec Brings Charge Detection Mass Spectrometry to the Global CRO Market
BioPharmaSpec is committed to providing the biopharmaceutical industry with state-of-the-art analytical technologies that enable confident, data-driven decision-making across the early biopharmaceutical development pathway. Through continuous investment in advanced instrumentation and scientific expertise, we deliver robust structural and physicochemical characterization across a wide range of biologics and complex molecules.
As part of this commitment, BioPharmaSpec has expanded its advanced analytical capabilities with the introduction of Charge Detection Mass Spectrometry (CDMS).
What is Charge Detection Mass Spectrometry?
Charge Detection Mass Spectrometry provides an innovative approach to the resolution, accurate mass measurement, and characterization of large molecular species that cannot be reliably analyzed using contemporary technologies.
CDMS determines both mass and charge for individual ions, delivering unprecedented insights into very large, complex, and heterogeneous structures such as:
- Drug conjugates – Mass distributions, DxR heterogeneity, and higher-order species
- Cell & gene products – Capsid & organelle distributions and population heterogeneity
- Protein aggregates and oligomers – Detection, resolution, and characterization of high-mass species
- Next-generation biologics – Complex and highly heterogeneous modalities that challenge conventional workflows
- Nanosphere technologies – Accurate sizing and detailed characterization
By introducing Xevo™ CDMS from Waters Corporation, BioPharmaSpec is opening its door to deeper characterization at early discovery, comparability, and late-stage development, supporting more confident decision-making when it matters most.
Looking Ahead
The introduction of CDMS marks another step in BioPharmaSpec’s ongoing commitment to enhancing analytical understanding and supporting the development of next-generation therapeutics. Our scientists look forward to sharing the first datasets, exploring new applications with our partners, and helping establish CDMS as a powerful new standard for advanced material characterization.
Connect with Our Experts
To learn how CDMS and other advanced mass spectrometry techniques can support your analytical strategy, contact our scientists or explore our full range of analytical services.